Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors-Reference-Cited by-同舟云学术

Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors

Published:2006-11 Issue:21 Volume:16 Page:5561-5566
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

El Abdellaoui Hassan,Varaprasad Chamakura V.N.S.,Barawkar Dinesh,Chakravarty Subrata,Maderna Andreas,Tam Robert,Chen Huanming,Allan Matt,Wu Jim Z.,Appleby Todd,Yan Shunqi,Zhang Weijian,Lang Stanley,Yao Nanhua,Hamatake Robert,Hong Zhi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. The MAPK signaling cascade

2. Progress Towards Therapeutic Small Molecule MEK Inhibitors for Use in Cancer Therapy

3. Mitogen-activated protein kinase pathways

4. Pyrrolopyridazine MEK inhibitors

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