Potent antagonists of the Kv1.5 potassium channel: Synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides-Reference-Cited by-同舟云学术

Potent antagonists of the Kv1.5 potassium channel: Synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides

Published:2006-11 Issue:22 Volume:16 Page:5897-5901
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Nanda Kausik K.,Brad Nolt M.,Cato Matthew J.,Kane Stefanie A.,Kiss Laszlo,Spencer Robert H.,Wang Jixin,Lynch Joseph J.,Regan Christopher P.,Stump Gary L.,Li Bing,White Rebecca,Yeh Suzie,Bogusky Michael J.,Bilodeau Mark T.,Dinsmore Christopher J.,Lindsley Craig W.,Hartman George D.,Wolkenberg Scott E.,Wesley Trotter B.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates 11Reprints are not available.

2. Cardiac channelopathies

3. Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents.

4. Antisense Oligodeoxynucleotides Directed Against Kv1.5 mRNA Specifically Inhibit Ultrarapid Delayed Rectifier K + Current in Cultured Adult Human Atrial Myocytes

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