Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide-Reference-Cited by-同舟云学术

Temozolomide analogs with improved brain/plasma ratios – Exploring the possibility of enhancing the therapeutic index of temozolomide

Published:2016-10 Issue:20 Volume:26 Page:5103-5109
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Rai Roopa,Banerjee Monali,Wong Darren H.,McCullagh Emma,Gupta Ashu,Tripathi Shailendra,Riquelme Eduardo,Jangir Ramnivas,Yadav Shyamraj,Raja Mohd.,Melkani Pankaj,Dixit Vikas,Patil Umesh,Shrivastava Ritesh,Middya Sandip,Olivares Felipe^ORCID,Guerrero Javier,Surya Arjun,Pham Son M.^ORCID,Bernales Sebastián,Protter Andrew A.,Hung David T.,Chakravarty Sarvajit

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas

2. Temozolomide: Mechanisms of Action, Repair and Resistance

3. Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Temozolomide in Malignant Glioma Patients

4. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

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