Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors-Reference-Cited by-同舟云学术

Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors

Published:2022-03 Issue: Volume:60 Page:128549
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ma Bin,Metrick Claire M.,Gu Chungang,Hoemberger Marc,Bajrami Bekim,Bame Eris,Huang Jiansheng,Mingueneau Michael,Murugan Paramasivam,Santoro Joseph C.,Tang Hao,Wang Ti,Hopkins Brian T.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

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5. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy;Honigberg;Proc Natl Acad Sci USA,2010

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