Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators-Reference-Cited by-同舟云学术

Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators

Published:2008-10 Issue:19 Volume:18 Page:5209-5212
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Albrecht Brian K.,Berry Virginia,Boezio Alessandro A.,Cao Lei,Clarkin Kristie,Guo Wenhong,Harmange Jean-Christophe,Hierl Markus,Huang Liyue,Janosky Brett,Knop Johannes,Malmberg Annika,McDermott Jeff S.,Nguyen Hung Q.,Springer Stephanie K.,Waldon Daniel,Woodin Katrina,McDonough Stefan I.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. The Structures of Neuronal Nicotinic Receptors

2. Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

3. Assembly and subunit diversity of nicotinic acetylcholine receptors

4. Central Nicotinic Receptors: Structure, Function, Ligands, and Therapeutic Potential

5. Neuroprotective effects of nicotine against salsolinol-induced cytotoxicity: Implications for parkinson’s disease

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent Advances in the Discovery of Nicotinic Acetylcholine Receptor Allosteric Modulators;Molecules;2023-01-28

2. Assessing potentiation of the (α4)3(β2)2 nicotinic acetylcholine receptor by the allosteric agonist CMPI;Journal of Biological Chemistry;2022-01

3. Potentiation of (α4)2(β2)3, but not (α4)3(β2)2, nicotinic acetylcholine receptors reduces nicotine self-administration and withdrawal symptoms;Neuropharmacology;2021-06

4. Allosterism of Nicotinic Acetylcholine Receptors: Therapeutic Potential for Neuroinflammation Underlying Brain Trauma and Degenerative Disorders;International Journal of Molecular Sciences;2020-07-12

5. Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats;Molecules;2020-06-25