Rational modification of the lead molecule: Enhancement in the anticancer and dihydrofolate reductase inhibitory activity-Reference-Cited by-同舟云学术

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Rational modification of the lead molecule: Enhancement in the anticancer and dihydrofolate reductase inhibitory activity

Published:2016-04 Issue:8 Volume:26 Page:1936-1940
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kaur Jagroop,Kaur Sukhmeet,Singh Palwinder

Funder

SERB-DST

DST

CSIR

University Grants Commission

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. World Health Statistic, 2012. World health Organisation Geneva, 2012.

2. Global cancer statistics

3. Cancer Facts and Figures, 2015, Atlanta, American Cancer Society; 2015.

4. A History of Cancer Chemotherapy

5. Triple-Negative Breast Cancer

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1. Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discovery;BMC Chemistry;2024-04-13

2. Screening of indole derivatives as the potent anticancer agents on dihydrofolate reductase: pharmaco-informatics and molecular dynamics simulation;Journal of Biomolecular Structure and Dynamics;2022-03-23

3. Rationally designed TNF-α inhibitors: Identification of promising cytotoxic agents;Bioorganic & Medicinal Chemistry Letters;2021-06

4. Two C(sp3)–F Bond Activation in a CF3 Group: ipso-Defluorinative Amination Triggered 1,3-Diamination of (Trifluoromethyl)alkenes with Indoles, Carbazoles, Pyrroles, and Sulfonamides;Organic Letters;2020-12-15

5. Structural tuning of acridones for developing anticancer agents targeting dihydrofolate reductase;Bioorganic & Medicinal Chemistry Letters;2019-10

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