Analysis of structure–activity relationships for the ‘B-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists-Reference-Cited by-同舟云学术

Analysis of structure–activity relationships for the ‘B-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists

Published:2005-09 Issue:18 Volume:15 Page:4143-4150
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lee Jeewoo,Jin Mi-Kyoung,Kang Sang-Uk,Kim Su Yeon,Lee Jiyoun,Shin Myoungyoup,Hwang Jaemin,Cho Sookhyun,Choi Yeon-Sil,Choi Hyun-Kyung,Kim Sung-Eun,Suh Young-Ger,Lee Yong-Sil,Kim Young-Ho,Ha Hee-Jin,Toth Attila,Pearce Larry V.,Tran Richard,Szabo Tamas,Welter Jacqueline D.,Lundberg Daniel J.,Wang Yun,Lazar Jozsef,Pavlyukovets Vladimir A.,Morgan Matthew A.,Blumberg Peter M.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin

2. Ruthenium red blocks the capsaicin-induced increase in intracellular calcium and activation of membrane currents in sensory neurones as well as the activation of peripheral nociceptors in vitro

3. Capsazocaine: A capsaicin-sensitive functional antagonist displays an argument on sensory capsaicin receptor

4. Attenuation of thermal nociception and hyperalgesia by VR1 blockers

5. The Arginine-Rich Hexapeptide R4W2Is a Stereoselective Antagonist at the Vanilloid Receptor 1: A Ca2+Imaging Study in Adult Rat Dorsal Root Ganglion Neurons

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