Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates-Reference-Cited by-同舟云学术

Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates

Published:2007-12 Issue:24 Volume:17 Page:6785-6789
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Mackman Richard L.,Boojamra Constantine G.,Prasad Vidya,Zhang Lijun,Lin Kuei-Ying,Petrakovsky Oleg,Babusis Darius,Chen James,Douglas Janet,Grant Deborah,Hui Hon C.,Kim Choung U.,Markevitch David Y.,Vela Jennifer,Ray Adrian,Cihlar Tomas

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Differential antiherpesvirus and antiretrovirus effects of the (S) and (R) enantiomers of acyclic nucleoside phosphonates: potent and selective in vitro and in vivo antiretrovirus activities of (R)-9-(2-phosphonomethoxypropyl)-2,6-diaminopurine

2. Phosphonates as analogues of natural phosphates

3. Anti-Human Immunodeficiency Virus Activity and Cellular Metabolism of a Potential Prodrug of the Acyclic Nucleoside Phosphonate 9- R -(2-Phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

4. Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue

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