Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors-Reference-Cited by-同舟云学术

Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors

Published:2007-12 Issue:24 Volume:17 Page:6816-6820
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Côté Bernard,Boulet Louise,Brideau Christine,Claveau David,Ethier Diane,Frenette Richard,Gagnon Marc,Giroux André,Guay Jocelyne,Guiral Sébastien,Mancini Joseph,Martins Evelyn,Massé Frédéric,Méthot Nathalie,Riendeau Denis,Rubin Joel,Xu Daigen,Yu Hongping,Ducharme Yves,Friesen Richard W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology

2. Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo.

3. Prostacyclin Antagonism Reduces Pain and Inflammation in Rodent Models of Hyperalgesia and Chronic Arthritis

4. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

5. Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

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