Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors-Reference-Cited by-同舟云学术

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Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors

Published:2018-02 Issue:4 Volume:28 Page:694-699
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Chitneni Satish K.,Reitman Zachary J.,Spicehandler Rebecca,Gooden David M.,Yan Hai,Zalutsky Michael R.

Funder

Southeastern Brain Tumor Foundation

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. IDH1 and IDH2 mutations in gliomas;Yan;N Engl J Med,2009

2. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome;Reitman;PNAS,2011

3. Isocitrate dehydrogenase mutations in gliomas;Waitkus;Neuro Oncol,2016

4. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate;Dang;Nature,2009

5. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations;Gross;J Exp Med,2010

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