Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design-Reference-Cited by-同舟云学术

Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design

Published:2006-06 Issue:12 Volume:16 Page:3310-3314
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Parks Daniel J.,LaFrance Louis V.,Calvo Raul R.,Milkiewicz Karen L.,José Marugán Juan,Raboisson Pierre,Schubert Carsten,Koblish Holly K.,Zhao Shuyuan,Franks Carol F.,Lattanze Jennifer,Carver Theodore E.,Cummings Maxwell D.,Maguire Diane,Grasberger Bruce L.,Maroney Anna C.,Lu Tianbao

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. The p53 pathway: positive and negative feedback loops

2. Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer

3. The p53-Mdm2 Pathway: Targets for the Development of New Anticancer Therapeutics

4. MDM2 Oncogene as a Novel Target for Human Cancer Therapy

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