Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors-Reference-Cited by-同舟云学术

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors

Published:2014-12 Issue:24 Volume:24 Page:5721-5726
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Duan James J.-W.,Lu Zhonghui,Jiang Bin,Yang Bingwei V.,Doweyko Lidia M.,Nirschl David S.,Haque Lauren E.,Lin Shuqun,Brown Gregory,Hynes John,Tokarski John S.,Sack John S.,Khan Javed,Lippy Jonathan S.,Zhang Rosemary F.,Pitt Sidney,Shen Guoxiang,Pitts William J.,Carter Percy H.,Barrish Joel C.,Nadler Steven G.,Salter-Cid Luisa M.,McKinnon Murray,Fura Aberra,Schieven Gary L.,Wrobleski Stephen T.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference17 articles.

1. JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease

2. Discovery and Development of Janus Kinase (JAK) Inhibitors for Inflammatory Diseases

3. Discovery of CP-690,550: A Potent and Selective Janus Kinase (JAK) Inhibitor for the Treatment of Autoimmune Diseases and Organ Transplant Rejection

4. Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis

5. Tofacitinib versus Methotrexate in Rheumatoid Arthritis

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