Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: High affinity and human/rat species-selective histamine H3 receptor antagonists-Reference-Cited by-同舟云学术

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Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: High affinity and human/rat species-selective histamine H3 receptor antagonists

Published:2013-12 Issue:23 Volume:23 Page:6415-6420
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Harusawa Shinya,Sawada Koichi,Magata Takuji,Yoneyama Hiroki,Araki Lisa,Usami Yoshihide,Hatano Kouta,Yamamoto Kouichi,Yamamoto Daisuke,Yamatodani Atsushi

Funder

Osaka University of Pharmaceutical Sciences

Scientific Research

JSPS

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference40 articles.

1. New concepts of histamine receptors and actions

2. Genomics Meets Histamine Receptors: New Subtypes, New Receptors

3. The role of histamine and the tuberomamillary nucleus in the nervous system

4. Constitutive activity of the histamine H3 receptor

5. Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

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2. Copper-Catalyzed Multicomponent Reactions of Intramolecular and Intermolecular Thiotrifluoromethylation of Alkenes: Access to CF₃–Containing 2-Iminothiazolidines and Isothioureas;Organic Letters;2022-09-27

3. A Unified Approach for the Synthesis of Isourea and Isothiourea from Isonitrile and N,N-Dibromoarylsulfonamides;The Journal of Organic Chemistry;2021-12-02

4. Guided rational design with scaffold hopping leading to novel histamine H3 receptor ligands;Bioorganic Chemistry;2021-12

5. Development of New Synthetic Reactions Using Hetero-Heavy Atoms and Their Application to Synthesis of Biofunctional Molecules;Chemical and Pharmaceutical Bulletin;2020-01-01

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