2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors-Reference-Cited by-同舟云学术

2-(2-Phenylmorpholin-4-yl)pyrimidin-4(3H)-ones; A new class of potent, selective and orally active glycogen synthase kinase-3β inhibitors

Published:2013-12 Issue:24 Volume:23 Page:6933-6937
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Fukunaga Kenji,Uehara Fumiaki,Aritomo Keiichi,Shoda Aya,Hiki Shinsuke,Okuyama Masahiro,Usui Yoshihiro,Watanabe Kazutoshi,Yamakoshi Koichi,Kohara Toshiyuki,Hanano Tokushi,Tanaka Hiroshi,Tsuchiya Susumu,Sunada Shinji,Saito Ken-Ichi,Eguchi Jun-ichi,Yuki Satoshi,Asano Shoichi,Tanaka Shinji,Mori Akiko,Yamagami Keiji,Baba Hiroshi,Horikawa Takashi,Fujimura Masatake

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

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2. Structure of tau protein and assembly into paired helical filaments

3. Alzheimer's Disease: Genes, Proteins, and Therapy

4. Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells

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