Design, synthesis, and biological evaluation of bone-targeted proteasome inhibitors for multiple myeloma-Reference-Cited by-同舟云学术

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Design, synthesis, and biological evaluation of bone-targeted proteasome inhibitors for multiple myeloma

Published:2013-12 Issue:23 Volume:23 Page:6455-6458
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Agyin Joseph K.,Santhamma Bindu,Roy Sudipa S.

Funder

National Cancer Institute

Kerr, and William & Ella Owens Research Foundations

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. BU-32: a novel proteasome inhibitor for breast cancer

2. A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B.

3. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

4. Active Site-directed Inhibitors of Rhodococcus 20 S Proteasome

5. Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation

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1. Engineering small-molecule and protein drugs for targeting bone tumors;Molecular Therapy;2024-05

2. Research strategies of small molecules as chemotherapeutics to overcome multiple myeloma resistance;European Journal of Medicinal Chemistry;2024-05

3. Bone-targeted bortezomib increases bone formation within Calvarial trans-sutural distraction osteogenesis;Bone;2023-04

4. Novel ferrocenylbisphosphonate hybrid compounds: Synthesis, characterization and potent activity against cancer cell lines;Bioorganic & Medicinal Chemistry;2022-03

5. Bone‐Targeted Bortezomib Inhibits Bortezomib‐Resistant Multiple Myeloma in Mice by Providing Higher Levels of Bortezomib in Bone;Journal of Bone and Mineral Research;2022-01-22

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