Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis-Reference-Cited by-同舟云学术

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis

Published:2007-07 Issue:14 Volume:17 Page:3953-3956
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hartzoulakis Basil,Rossiter Sharon,Gill Herpreet,O’Hara Bernard,Steinke Emily,Gane Paul J.,Hurtado-Guerrero Ramon,Leiper James M.,Vallance Patrick,Rust Judith Murray,Selwood David L.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Determination of protein function, evolution and interactions by structural genomics

2. The guanidino-group modifying enzymes: Structural basis for their diversity and commonality

3. A Fluoroacetamidine-Based Inactivator of Protein Arginine Deiminase 4: Design, Synthesis, and in Vitro and in Vivo Evaluation

4. Disruption of methylarginine metabolism impairs vascular homeostasis

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances in DDAH1 inhibitor design and discovery: insights from structure–activity relationships and X-ray crystal structures;RSC Advances;2024

2. Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling;Scientific Reports;2022-06-07

3. Structure and Function of Enzymes Involved in the Biosynthesis of Tropane Alkaloids;Tropane Alkaloids;2021

4. Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer;Frontiers in Oncology;2020-01-09

5. The Second Life of Methylarginines as Cardiovascular Targets;International Journal of Molecular Sciences;2019-09-17