4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation-Reference-Cited by-同舟云学术

4-Aryl-5-cyano-2-aminopyrimidines as VEGF-R2 inhibitors: Synthesis and biological evaluation

Published:2007-06 Issue:12 Volume:17 Page:3266-3270
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hughes Terry V.,Emanuel Stuart L.,Beck Amanda K.,Wetter Steven K.,Connolly Peter J.,Karnachi Prabha,Reuman Michael,Seraj Jabed,Fuentes-Pesquera Angel R.,Gruninger Robert H.,Middleton Steven A.,Lin Ronghui,Davis Jeremy M.,Moffat David F.C.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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3. Blockade of Vascular Endothelial Cell Growth Factor Receptor Signaling Is Sufficient to Completely Prevent Retinal Neovascularization

4. A Vascular Endothelial Growth Factor Receptor-2 Kinase Inhibitor Potentiates the Activity of the Conventional Chemotherapeutic Agents Paclitaxel and Doxorubicin in Tumor Xenograft Models

5. Batchelor, M. J.; Moffat, D. F. C.; Davis, J. M.; Hutchings, M. C. U.S. Patent 6,579,983, 2003.

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