Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors-Reference-Cited by-同舟云学术

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Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors

Published:2010-12 Issue:24 Volume:20 Page:7216-7221
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Zhao Lianyun,Zhang Yingxin,Dai Chaoyang,Guzi Timothy,Wiswell Derek,Seghezzi Wolfgang,Parry David,Fischmann Thierry,Siddiqui M. Arshad

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Sequence-Selective DNA Recognition: Natural Products and Nature’s Lessons

2. DNA and its associated processes as targets for cancer therapy

3. Emerging cancer therapeutic opportunities target DNA-repair systems

4. Targeting the checkpoint kinases: chemosensitization versus chemoprotection

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2. The pyridazine heterocycle in molecular recognition and drug discovery;Medicinal Chemistry Research;2023-03-15

3. Efficient Synthesis of (S)-1-Boc-3-aminopiperidine in a Continuous Flow System Using ω-Transaminase-Immobilized Amino-Ethylenediamine-Modified Epoxide Supports;Organic Process Research & Development;2022-04-15

4. Design, synthesis and evaluation of novel thienopyridazine derivatives as Chk1/2 inhibitors;Bioorganic Chemistry;2022-04

5. Identification of CHK1 Kinase Inhibitors Using Structure-Based Pharmacophore Modeling and Molecular Docking;Indian Journal of Pharmaceutical Sciences;2020

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