Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly

Author:

Fader Lee D.,Bethell Richard,Bonneau Pierre,Bös Michael,Bousquet Yves,Cordingley Michael G.,Coulombe René,Deroy Patrick,Faucher Anne-Marie,Gagnon Alexandre,Goudreau Nathalie,Grand-Maître Chantal,Guse Ingrid,Hucke Oliver,Kawai Stephen H.,Lacoste Jean-Eric,Landry Serge,Lemke Christopher T.,Malenfant Eric,Mason Stephen,Morin Sébastien,O’Meara Jeff,Simoneau Bruno,Titolo Steve,Yoakim Christiane

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Entry inhibitors in the treatment of HIV-1 infection

2. Strand transfer inhibitors of HIV-1 integrase: Bringing IN a new era of antiretroviral therapy

3. Titolo, S., Mercier, J.-F.; Wardrop, E.; von Schwedler, U.; Goudreau, N.; Lemke, C.; Faucher, A.-M.; Yoakim, C.; Simoneau, .B.; Sundquist, W. I.; Mason, S. ‘Discovery of potent HIV-1 capsid assembly inhibitors.’ 17th Conference on Retroviruses and Opportunistic Infections 2010. Oral abstract 50.

4. Novel approaches to inhibiting HIV-1 replication

5. The structural biology of HIV assembly

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