Discovery, characterization and biological evaluation of a novel ( R )-4,4-difluoropiperidine scaffold as dopamine receptor 4 (D 4 R) antagonists-Reference-Cited by-同舟云学术

Discovery, characterization and biological evaluation of a novel ( R )-4,4-difluoropiperidine scaffold as dopamine receptor 4 (D 4 R) antagonists

Published:2016-12 Issue:23 Volume:26 Page:5757-5764
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Jeffries Daniel E.,Witt Jonathan O.,McCollum Andrea L.,Temple Kayla J.,Hurtado Miguel A.,Harp Joel M.^ORCID,Blobaum Anna L.,Lindsley Craig W.,Hopkins Corey R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Dopamine receptors and brain function

2. Update 1 of: Recent Progress in Development of Dopamine Receptor Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders

3. The Neurobiology of Dopamine Signaling

4. Multiple dopamine D4 receptor variants in the human population

5. Dopamine and psychosis: Theory, pathomechanisms and intermediate phenotypes

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