Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus-Reference-Cited by-同舟云学术

Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus

Published:2017-05 Issue:9 Volume:27 Page:2063-2068
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Xu Jiayi,Lin Songnian,Myers Robert W.,Trujillo Maria E.,Pachanski Michele J.,Malkani Sunita,Chen Hsuan-shen,Chen Zhesheng,Campbell Brian,Eiermann George J.,Elowe Nadine,Farrer Brian T.,Feng Wen,Fu Qinghong,Kats-Kagan Roman,Kavana Michael,McMasters Daniel R.,Mitra Kaushik,Tong Xinchun,Xu Libo,Zhang Fengqi,Zhang Rui,Addona George H.,Berger Joel P.,Zhang Bei,Parmee Emma R.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Glucose Homeostasis and Insulin Resistance;Szablewski,2011

2. Glucokinase and molecular aspects of liver glycogen metabolism

3. A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm

4. Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

5. Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

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