Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors-Reference-Cited by-同舟云学术

Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors

Published:2009-12 Issue:23 Volume:19 Page:6519-6523
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Berger Dan M.,Torres Nancy,Dutia Minu,Powell Dennis,Ciszewski Greg,Gopalsamy Ariamala,Levin Jeremy I.,Kim Kyung-Hee,Xu Weixin,Wilhelm James,Hu YongBo,Collins Karen,Feldberg Larry,Kim Steven,Frommer Eileen,Wojciechowicz Donald,Mallon Robert

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference9 articles.

1. Mutations of the BRAF gene in human cancer

2. RAF/RAS oncogenes and mismatch-repair status

3. BRAF mutation in thyroid cancer

4. Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors

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