Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)-Reference-Cited by-同舟云学术

Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1)

Published:2016-05 Issue:10 Volume:26 Page:2470-2474
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Guo Junqing,Watterson Scott H.,Spergel Steven H.,Kempson James,Langevine Charles M.,Shen Ding Ren,Yarde Melissa,Cvijic Mary Ellen,Banas Dana,Liu Richard,Suchard Suzanne J.,Gillooly Kathleen,Taylor Tracy,Rex-Rabe Sandra,Shuster David J.,McIntyre Kim W.,Cornelius Georgia,D’Arienzo Celia,Marino Anthony,Balimane Praveen,Salter-Cid Luisa,McKinnon Murray,Barrish Joel C.,Carter Percy H.,Pitts William J.,Xie Jenny,Dyckman Alaric J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. Physiological and pathological actions of sphingosine 1-phosphate

2. In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights

3. Dual Roles of Tight Junction-associated Protein, Zonula Occludens-1, in Sphingosine 1-Phosphate-mediated Endothelial Chemotaxis and Barrier Integrity

4. Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

5. Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

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