An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model-Reference-Cited by-同舟云学术

An orally available, brain-penetrant CAMKK2 inhibitor reduces food intake in rodent model

Published:2018-06 Issue:10 Volume:28 Page:1958-1963
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Price Daniel J.,Drewry David H.,Schaller Lee T.,Thompson Brian D.,Reid Paul R.,Maloney Patrick R.,Liang Xi,Banker Periette,Buckholz Richard G.,Selley Paula K.,McDonald Octerloney B.,Smith Jeffery L.,Shearer Todd W.,Cox Richard F.,Williams Shawn P.,Reid Robert A.,Tacconi Stefano^ORCID,Faggioni Federico,Piubelli Chiara,Sartori Ilaria,Tessari Michela,Wang Tony Y.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Obesity: Preventing and Managing the Global Epidemic. WHO Technical Report Series, 894. The World Health Organization, 2000.

2. AMPK: a nutrient and energy sensor that maintains energy homeostasis

3. Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

4. The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

5. Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Quantum-assisted fragment-based automated structure generator (QFASG) for small molecule design: an in vitro study;Frontiers in Chemistry;2024-04-03

2. 14‐3‐3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C‐terminal helices;Protein Science;2023-10-20

3. Synthesis of C3,C6-Diaryl 7-Azaindoles via One-Pot Suzuki–Miyaura Cross-Coupling Reaction and Evaluation of Their HIV-1 Integrase Inhibitory Activity;ACS Omega;2023-02-22

4. SGC-CAMKK2-1: A Chemical Probe for CAMKK2;Cells;2023-01-11

5. SGC-CAMKK2-1: A chemical probe for CAMKK2;2022-10-20