3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization-Reference-Cited by-同舟云学术

3-Benzyl-1,3-oxazolidin-2-ones as mGluR2 positive allosteric modulators: Hit-to lead and lead optimization

Published:2009-05 Issue:9 Volume:19 Page:2524-2529
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Duplantier Allen J.,Efremov Ivan,Candler John,Doran Angela C.,Ganong Alan H.,Haas Jessica A.,Hanks Ashley N.,Kraus Kenneth G.,Lazzaro John T.,Lu Jiemin,Maklad Noha,McCarthy Sheryl A.,O’Sullivan Theresa J.,Rogers Bruce N.,Siuciak Judith A.,Spracklin Douglas K.,Zhang Lei

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

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4. Anxiolytic effects of a novel group II metabotropic glutamate receptor agonist (LY354740) in the fear-potentiated startle paradigm in humans

5. In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders

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