Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors-Reference-Cited by-同舟云学术

Discovery and optimization of thieno[2,3-d]pyrimidines as B-Raf inhibitors

Published:2012-01 Issue:1 Volume:22 Page:747-752
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Packard Garrick K.,Papa Patrick,Riggs Jennifer R.,Erdman Paul,Tehrani Lida,Robinson Dale,Harris Roy,Shevlin Graziella,Perrin-Ninkovic Sophie,Hilgraf Robert,McCarrick Margaret A.,Tran Tam,Fleming Yuedi,Bai April,Richardson Samantha,Katz Jason,Tang Yang,Leisten Jim,Moghaddam Mehran,Cathers Brian,Zhu Dan,Sakata Steven

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference7 articles.

1. Targeting the MAPK pathway in melanoma: Why some approaches succeed and other fail

2. Recent Advances in the Research and Development of B-Raf Inhibitors

3. For experimental details of compound synthesis and in vitro assays please see: McKenna, J.; Papa, P. W.; Sakata, S. T.; Erdman, P. E.; Packard, G. K. WO 2007/084560.

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