Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa-Reference-Cited by-同舟云学术

Orally bioavailable amine-linked macrocyclic inhibitors of factor XIa

Published:2020-02 Issue:4 Volume:30 Page:126949
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Fang Tianan,Corte James R.,Gilligan Paul J.,Jeon Yoon,Osuna Honey,Rossi Karen A.,Myers Joseph E.,Sheriff Steven,Lou Zhen,Zheng Joanna J.,Harper Timothy W.,Bozarth Jeffrey M.,Wu Yiming,Luettgen Joseph M.,Seiffert Dietmar A.,Wexler Ruth R.,Lam Patrick Y.S.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

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2. Overview of the New Oral Anticoagulants

3. The design and rationale for the Acute Medically Ill Venous Thromboembolism Prevention with Extended Duration Betrixaban (APEX) study

4. Dabigatran versus Warfarin in Patients with Atrial Fibrillation

5. Factor XI as a target for antithrombotic therapy

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1. Factor XIa Inhibitors in Anticoagulation Therapy: Recent Advances and Perspectives;Journal of Medicinal Chemistry;2023-04-10

2. RECENT PROGRESS IN FACTOR XI/XIA INHIBITOR DISCOVERY;2022 Medicinal Chemistry Reviews;2022-12-21

3. Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy;Journal of Medicinal Chemistry;2021-09-08

4. Studies on fragment-based design of allosteric inhibitors of human factor XIa;Bioorganic & Medicinal Chemistry;2020-12

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