Design, synthesis and preliminary biological evaluation of C-8 substituted guanine derivatives as small molecular inhibitors of FGFRs-Reference-Cited by-同舟云学术

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Design, synthesis and preliminary biological evaluation of C-8 substituted guanine derivatives as small molecular inhibitors of FGFRs

Published:2015-04 Issue:7 Volume:25 Page:1556-1560
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Ye Faqing,Chen Liangfang,Hu Lichuan,Xiao Tong,Yu Shufang,Chen Di,Wang Yu,Liang Guang,Liu Zhiguo,Wang Sicen

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Cellular signaling by fibroblast growth factor receptors

2. Fibroblast growth factor signalling: from development to cancer

3. Small molecule inhibition of fibroblast growth factor receptors in cancer

4. Molecular Pathways: Fibroblast Growth Factor Signaling: A New Therapeutic Opportunity in Cancer

5. Synthesis and Structure−Activity Relationships of Soluble 7-Substituted 3-(3,5-Dimethoxyphenyl)-1,6-naphthyridin-2-amines and Related Ureas as Dual Inhibitors of the Fibroblast Growth Factor Receptor-1 and Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinases

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular modeling of pyrrolo-pyrimidine based analogs as potential FGFR1 inhibitors: a scientific approach for therapeutic drugs;Journal of Biomolecular Structure and Dynamics;2023-03-10

2. Design, Synthesis and Biological Evaluation: 5-amino-1H-pyrazole-1- carbonyl derivatives as FGFR Inhibitors;Letters in Drug Design & Discovery;2020-10-23

3. Recent advance in the development of novel, selective and potent FGFR inhibitors;European Journal of Medicinal Chemistry;2020-01

4. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3;European Journal of Medicinal Chemistry;2019-10

5. Identification of protein kinase fibroblast growth factor receptor 1 (FGFR1) inhibitors among the derivatives of 5-(5,6-dimethoxybenzimidazol-1-yl)-3-hydroxythiophene-2-carboxylic acid;Monatshefte für Chemie - Chemical Monthly;2019-09-28

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