Discovery and optimization of covalent Bcl-xL antagonists-Reference-Cited by-同舟云学术

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Discovery and optimization of covalent Bcl-xL antagonists

Published:2019-12 Issue:23 Volume:29 Page:126682
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Mukherjee Herschel,Su Nancy,Belmonte Matthew A.,Hargreaves David,Patel Joe,Tentarelli Sharon,Aquila Brian,Grimster Neil P.

Funder

AstraZeneca PostDoc Program

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

1. Targeting protein-protein interactions for therapeutic intervention: a challenge for the future;Zinzalla;Future Med Chem,2009

2. Inhibition of alpha-helix-mediated protein-protein interactions using designed molecules;Azzarito;Nat Chem,2013

3. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream;Arkin;Nat Rev Drug Discov,2004

4. Targeting protein-protein interactions by rational design: mimicry of protein surfaces;Fletcher;J R Soc Interface,2006

5. Unraveling hot spots in binding interfaces: progress and challenges;DeLano;Curr Opin Struct Biol,2002

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