Selective deuteration of bupropion slows epimerization and reduces metabolism-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Selective deuteration of bupropion slows epimerization and reduces metabolism

Published:2022-11 Issue: Volume:76 Page:129009
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Shi Yuanyuan,Dinh Jean,Pelletier Robert,Raccor Brianne,Yusuff Naeem,Morgan Adam J.,Harbeson Scott,Uttamsingh Vinita,Totah Rheem A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Chemical Kinetics;Ladler,1987

2. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals;Russak;Ann Pharmacother,2019

3. Altering metabolic profiles of drugs by precision deuteration: Reducing mechanism-based inhibition of CYP2D6 by Paroxetine;Uttamsingh;J Pharmacol Exp Ther,2015

4. U.S. Food & Drug Administration, Drugs@FDA: FDA Approved Drug ProductS, AUSTEDO (DEUTETRABENAZINE), 2017,in:https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event¼overview.process&varApplNo¼208082.

5. Altering metabolic profiles of drugs by precision deuteration 2: Discovery of a deuterated analog of ivacaftor with differentiated pharmacokinetics for clinical development;Harbeson;J Pharmacol Exp Ther,2017

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances in late‐stage selective deuteration for drug development;Applied Organometallic Chemistry;2024-07

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP