Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor-Reference-Cited by-同舟云学术

Lead identification of novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent heparanase-1 inhibitor

Published:2023-01 Issue: Volume:79 Page:129050
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Imai Yudai,Wakasugi Daisuke,Suzuki Ryo,Kato Sota,Sugisaki Mami,Mima Masashi,Miyagawa Hiroh,Endo Mayumi,Fujimoto Natsuko,Fukunaga Takuya,Kato Sayaka,Kuroda Shoichi,Takahashi Teisuke,Kakinuma Hiroyuki

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. 1H NMR spectroscopic studies establish that heparanase is a retaining glycosidase;Wilson;Biochem Biophys Res Commun,2014

2. Structural characterization of human heparanase reveals insights into substrate recognition;Liang;Nat Struct Mol Biol,2015

3. Heparanase in glomerular diseases;van den Hoven;Kidney Int,2007

4. The role of heparanase and the endothelial glycocalyx in the development of proteinuria;Garsen;Nephrol Dial Transplant,2014

5. Heparanase is essential for the development of acute experimental glomerulonephritis;Garsen;Am J Pathol,2016

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. New type of tri‐pyridyl inhibitor‐loaded polyaniline nanospheres for durable protection anticorrosion coatings;Journal of Applied Polymer Science;2024-03-12

2. Discovery of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach;Bioorganic & Medicinal Chemistry Letters;2024-01

3. Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor;Bioorganic & Medicinal Chemistry;2023-10

4. Synthesis of the Key Saccharide Fragments of the Glucuronic Acid-Containing Repeat Unit of Pentosan Polysulfate, a Heparin Sulfate Mimetic;SynOpen;2023-07-10

5. New compounds based on 1H-pyrrolo[2,3-b] pyridine as potent TNIK inhibitors against colorectal cancer cells. Molecular modeling studies;MOROC J CHEM;2023