Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa-Reference-Cited by-同舟云学术

Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa

Published:2006-10 Issue:19 Volume:16 Page:5176-5182
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Li Yun-Long,Fevig John M.,Cacciola Joseph,Buriak Joseph,Rossi Karen A.,Jona Janan,Knabb Robert M.,Luettgen Joseph M.,Wong Pancras C.,Bai Stephen A.,Wexler Ruth R.,Lam Patrick Y.S.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. New anticoagulants

2. Rationale for the use of antifactor Xa in the treatment and prevention of venous and arterial thromboembolic events

3. The Dynamics of Thrombin Formation

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