Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei-Reference-Cited by-同舟云学术

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Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei

Published:2017-01 Issue:1 Volume:27 Page:45-50
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Schirmeister Tanja,Schmitz Janina,Jung Sascha,Schmenger Torsten,Krauth-Siegel R. Luise,Gütschow Michael

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Transferrin: endocytosis and cell signaling in parasitic protozoa;Reyes-López,2015

2. The Inhibition of Cysteine Proteases Rhodesain and TbCatB: A Valuable Approach to Treat Human African Trypanosomiasis

3. Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors

4. Cysteine proteases as therapeutic targets: does selectivity matter? A systematic review of calpain and cathepsin inhibitors

5. Cathepsin B Inhibitors: Combining Dipeptide Nitriles with an Occluding Loop Recognition Element by Click Chemistry

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1. Exploring the latest breakthroughs in rhodesain inhibitors for African trypanosomiasis;Medicinal Chemistry Research;2024-02-02

2. Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options;Pharmaceuticals;2023-07-19

3. An update on the discovery and development of reversible covalent inhibitors;Medicinal Chemistry Research;2023-04-29

4. Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense;International Journal of Molecular Sciences;2022-11-21

5. The Discovery of Small Allosteric and Active Site Inhibitors of the SARS-CoV-2 Main Protease via Structure-Based Virtual Screening and Biological Evaluation;Molecules;2022-10-09

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