Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase-Reference-Cited by-同舟云学术

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Discovery and initial optimization of alkoxyanthranilic acid derivatives as inhibitors of HCV NS5B polymerase

Published:2017-01 Issue:2 Volume:27 Page:295-298
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Parcella Kyle,Nickel Andrew,Beno Brett R.,Sheriff Steven,Wan Changhong,Wang Ying-Kai,Roberts Susan B.,Meanwell Nicholas A.,Kadow John F.

Funder

Hauptman-Woodward Medical Research Institute

U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference10 articles.

1. Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence;Hanafiah;Hepatology,2013

2. Centers for Disease Control and Prevention: Viral Hepatitis-Hepatitis C. www.cdc.gov/hepatitis/hcv. Accessed 10/26/15.

3. Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase;Sofia;J Med Chem,2012

4. The HCV revolution did not happen overnight;Kwong;ACS Med Chem Lett,2014

5. Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid;Pfefferkorn;Bioorg Med Chem Lett,2005

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1. Distinct Characteristic Binding Modes of Benzofuran Core Inhibitors to Diverse Genotypes of Hepatitis C Virus NS5B Polymerase: A Molecular Simulation Study;International Journal of Molecular Sciences;2024-07-23

2. A Theoretical Study on the Binding Mechanism of the Benzofuran Core Pan-Genotypic Hcv Ns5b Polymerase Inhibitors;2024

3. Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective;European Journal of Medicinal Chemistry;2022-10

4. The synthesis of 3-(het)aryl-6,7-dihydro-5H-[1,2,4]-triazolo[3,4-a][2]benzazepines;Chemistry of Heterocyclic Compounds;2021-01

5. A General Way to Construct Arene-Fused Seven-Membered Nitrogen Heterocycles;European Journal of Organic Chemistry;2018-01-18

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