Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin-Reference-Cited by-同舟云学术

Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin

Published:2007-06 Issue:12 Volume:17 Page:3384-3387
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Biftu Tesfaye,Scapin Giovanna,Singh Suresh,Feng Dennis,Becker Joe W.,Eiermann George,He Huaibing,Lyons Kathy,Patel Sangita,Petrov Aleksandr,Sinha-Roy Ranabir,Zhang Bei,Wu Joseph,Zhang Xiaoping,Doss George A.,Thornberry Nancy A.,Weber Ann E.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

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