“PROTAC” modified dihydroquinolizinones (DHQs) that cause degradation of PAPD-5 and inhibition of hepatitis A virus and hepatitis B virus, in vitro

Author:

Li YouORCID,Hwang NickyORCID,Snedeker Andrew,Lemon Stanley M.,Noe Daisy,Sun LirenORCID,Clement Jason A.,Zhou Tianlun,Tang Liudi,Block Timothy,Du YanmingORCID

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Elsevier BV

Reference34 articles.

1. World Health Organization. WHO fact sheets on hepatitis. Accessed 27 January 2024. https://www.who.int/news-room/fact-sheets/detail/hepatitis.

2. Centers for Disease Control and Prevention USA. Person-to-person outbreaks of hepatitis A across the United States. Accessed 27 January 2024. https://www.cdc.gov/hepatitis/outbreaks/2017March-HepatitisA.htm.

3. Factors associated with hepatitis a mortality during person-to-person outbreaks: a matched case-control study-United States, 2016–2019;Hofmeister;Hepatology,2021

4. Therapeutic strategies for hepatitis B virus infection: towards a cure;Fanning;Nature Reviews. Drug Discovery,2019

5. Antiviral therapy for chronic hepatitis B viral infection in adults: a systematic review and meta-analysis;Lok;Hepatology,2016

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