Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant-Reference-Cited by-同舟云学术

Discovery of piperidine ethers as selective orexin receptor antagonists (SORAs) inspired by filorexant

Published:2015-02 Issue:3 Volume:25 Page:444-450
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Raheem Izzat T.,Breslin Michael J.,Bruno Joseph,Cabalu Tamara D.,Cooke Andrew,Cox Christopher D.,Cui Donghui,Garson Susan,Gotter Anthony L.,Fox Steven V.,Harrell C. Meacham,Kuduk Scott D.,Lemaire Wei,Prueksaritanont Thomayant,Renger John J.,Stump Craig,Tannenbaum Pamela L.,Williams Peter D.,Winrow Christopher J.,Coleman Paul J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

2. Orexins and Orexin Receptors: A Family of Hypothalamic Neuropeptides and G Protein-Coupled Receptors that Regulate Feeding Behavior

3. The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

4. Narcolepsy in orexin Knockout Mice

5. Reduced Number of Hypocretin Neurons in Human Narcolepsy

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