Characterization of TRIF selectivity in the AGP class of lipid A mimetics: Role of secondary lipid chains-Reference-Cited by-同舟云学术

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Characterization of TRIF selectivity in the AGP class of lipid A mimetics: Role of secondary lipid chains

Published:2015-02 Issue:3 Volume:25 Page:547-553
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Khalaf Juhienah K.,Bowen William S.,Bazin Hélène G.,Ryter Kendal T.,Livesay Mark T.,Ward Jon R.,Evans Jay T.,Johnson David A.

Funder

GlaxoSmithKline Biologicals SA

National Institutes of Allergy and Infectious Diseases

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference45 articles.

1. Therapeutics targeting the innate immune system

2. Use of defined TLR ligands as adjuvants within human vaccines

3. Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction

4. The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

5. Differential Induction of the Toll-Like Receptor 4-MyD88-Dependent and -Independent Signaling Pathways by Endotoxins

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1. Diamino Allose Phosphates: Novel, Potent, and Highly Stable Toll-like Receptor 4 Agonists;Journal of Medicinal Chemistry;2023-10-17

2. Review: Current trends, challenges, and success stories in adjuvant research;Frontiers in Immunology;2023-01-19

3. Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation;Pharmaceutics;2021-04-06

4. Immunobiology and application of toll-like receptor 4 agonists to augment host resistance to infection;Pharmacological Research;2019-12

5. Recent progress in the discovery of myeloid differentiation 2 (MD2) modulators for inflammatory diseases;Drug Discovery Today;2018-06

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