Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements

Author:

Paget Steven D.,Boggs Christine M.,Foleno Barbara D.,Goldschmidt Raul M.,Hlasta Dennis J.,Weidner-Wells Michele A.,Werblood Harvey M.,Bush Karen,Macielag Mark J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. Spectrum and potency evaluation of a new oxazolidinone, linezolid: report from the SENTRY Antimicrobial Surveillance Program, 1998–2000

2. Treatment Options for Vancomycin- Resistant Enterococcal Infections

3. Jacoby, G.; Bush, K. In Frontiers in Antimicrobial Resistance: a Tribute to Stuart B. Levy; White, D. G., Alekshun, M. N., McDermott, P. F., Eds.; ASM Press: Washington, DC, 2005; Chapter 5, pp 53–65.

4. Synthesis and antibacterial activity of pyrroloaryl-substituted oxazolidinones

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