Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studies-Reference-Cited by-同舟云学术

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Tricyclic sulfones as orally active γ-secretase inhibitors: Synthesis and structure–activity relationship studies

Published:2010-06 Issue:12 Volume:20 Page:3632-3635
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sasikumar T.K.,Qiang Li,Burnett Duane A.,Cole David,Xu Ruo,Li Hongmei,Greenlee William J.,Clader John,Zhang Lili,Hyde Lynn

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Amyloid deposition as the central event in the aetiology of Alzheimer's disease

2. γ-secretase inhibitors for the treatment of Alzheimer's disease

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