Discovery of triazines as potent, selective and orally active PDE4 inhibitors-Reference-Cited by-同舟云学术

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Discovery of triazines as potent, selective and orally active PDE4 inhibitors

Published:2013-08 Issue:15 Volume:23 Page:4308-4314
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Gewald Rainer,Grunwald Christian,Egerland Ute

Funder

European Fund for Regional Development (EFRE)

Free State of Saxony

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

2. Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling

3. Phosphodiesterase: overview of protein structures, potential therapeutic applications and recent progress in drug development

4. Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

5. Future directions in phosphodiesterase drug discovery

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1. PDE4D: A Multipurpose Pharmacological Target;International Journal of Molecular Sciences;2024-07-24

2. Development of White Cabbage, Coffee, and Red Onion Extracts as Natural Phosphodiesterase-4B (PDE4B) Inhibitors for Cognitive Dysfunction: In Vitro and In Silico Studies;Advances in Pharmacological and Pharmaceutical Sciences;2024-05-21

3. Hydroxytakakiamide and Other Constituents from a Marine Sponge-Associated Fungus Aspergillus fischeri MMERU23, and Antinociceptive Activity of Ergosterol Acetate, Acetylaszonalenin and Helvolic Acid;Marine Drugs;2024-02-20

4. Discovery of 2-(Methylcarbonylamino) thiazole as PDE4 inhibitors via virtual screening and biological evaluation;Journal of Molecular Graphics and Modelling;2023-11

5. Structural insights into the lead identification of sub-type selective PDE4B inhibitors from plant bioactive molecule analogues;Journal of Molecular Liquids;2023-11

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