The design, synthesis and structure–activity relationships of novel isoindoline-based histone deacetylase inhibitors-Reference-Cited by-同舟云学术

The design, synthesis and structure–activity relationships of novel isoindoline-based histone deacetylase inhibitors

Published:2011-08 Issue:16 Volume:21 Page:4909-4912
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Shultz Michael,Fan Jianmei,Chen Christine,Cho Young Shin,Davis Nicole,Bickford Sheri,Buteau Kristen,Cao Xueying,Holmqvist Mats,Hsu Meier,Jiang Lei,Liu Gang,Lu Qiang,Patel Chetan,Suresh Joghee Raju,Selvaraj Mannangatti,Urban Laszlo,Wang Ping,Yan-Neale Yan,Whitehead Lewis,Zhang Haiyan,Zhou Liping,Atadja Peter

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation

2. Histone deacetylation in epigenetics: An attractive target for anticancer therapy

3. A phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia

4. Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies

5. A Phase I and Pharmacokinetic Study of the Oral Histone Deacetylase Inhibitor, MS-275, in Patients with Refractory Solid Tumors and Lymphomas

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