The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations-Reference-Cited by-同舟云学术

The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations

Published:2008-05 Issue:9 Volume:18 Page:2959-2966
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Tucker Thomas J.,Saggar Sandeep,Sisko John T.,Tynebor Robert M.,Williams Theresa M.,Felock Peter J.,Flynn Jessica A.,Lai Ming-Tain,Liang Yuexia,McGaughey Georgia,Liu Meiquing,Miller Mike,Moyer Gregory,Munshi Vandna,Perlow-Poehnelt Rebecca,Prasad Sridhar,Sanchez Rosa,Torrent Maricel,Vacca Joseph P.,Wan Bang-Lin,Yan Youwei

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference21 articles.

1. Structural and biochemical effects of human immunodeficiency virus mutants resistant to non-nucleoside reverse transcriptase inhibitors

2. Recent Advances in the Development of Next Generation Non-nucleoside Reverse Transcriptase Inhibitors

3. Tetrazole thioacetanilides: Potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant

4. Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase

5. Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases

Cited by 57 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current status of the small molecule anti-HIV drugs in the pipeline or recently approved;Bioorganic & Medicinal Chemistry;2024-09

2. Doravirine (Pifeltro): A Third‐Generation Non‐Nucleoside Reverse Transcriptase Inhibitor as a Treatment of HIV ‐1 Infection;Chemistry and Pharmacology of Drug Discovery;2024-08-16

3. Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase;European Journal of Medicinal Chemistry;2023-12

4. Fluorine in anti-HIV drugs approved by FDA from 1981 to 2023;European Journal of Medicinal Chemistry;2023-10

5. Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1;Science Translational Medicine;2023-02-22