Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors-Reference-Cited by-同舟云学术

Pyrazolo-pyrimidines: A novel heterocyclic scaffold for potent and selective p38α inhibitors

Published:2008-04 Issue:8 Volume:18 Page:2652-2657
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Das Jagabandhu,Moquin Robert V.,Pitt Sidney,Zhang Rosemary,Shen Ding Ren,McIntyre Kim W.,Gillooly Kathleen,Doweyko Arthur M.,Sack John S.,Zhang Hongjian,Kiefer Susan E.,Kish Kevin,McKinnon Murray,Barrish Joel C.,Dodd John H.,Schieven Gary L.,Leftheris Katerina

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Deficiency of the Stress Kinase P38α Results in Embryonic Lethality

2. Coordinate activation of endogenous p38a, β, γ, and δ by inflammatory stimuli

3. The Biology of p38 Kinase: A Central Role in Inflammation

4. The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

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