Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase-Reference-Cited by-同舟云学术

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Design and evaluation of novel tetracyclic benzofurans as palm site allosteric inhibitors of HCV NS5B polymerase

Published:2019-12 Issue:24 Volume:29 Page:126104
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Hong,Dai Xing,He Shuwen,Brockunier Linda,Marcantonio Karen,Ludmerer Steven W.,Li Fangbiao,Feng Kung-I,Nargund Ravi P.,Palani Anandan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference16 articles.

1. The epidemiology of hepatitis C infection in the United States;Rustogi;J Gastroenterol,2007

2. Unravelling hepatitis C virus replication from genome to function;Lindenbach;Nature,2005

3. Understanding the hepatitis C virus life cycles paves the way for highly effetive therapies;Scheel;Nat Med,2013

4. Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus;Behrens;EMBO J,1996

5. Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus;Bressanelli;Proc Nat Acad Sci,1999

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Distinct Characteristic Binding Modes of Benzofuran Core Inhibitors to Diverse Genotypes of Hepatitis C Virus NS5B Polymerase: A Molecular Simulation Study;International Journal of Molecular Sciences;2024-07-23

2. Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective;European Journal of Medicinal Chemistry;2022-10

3. Multi-step parallel synthesis enabled optimization of benzofuran derivatives as pan-genotypic non-nucleoside inhibitors of HCV NS5B;Bioorganic & Medicinal Chemistry Letters;2020-04

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