Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD-Reference-Cited by-同舟云学术

Discovery of 5-(2-chloro-4′-(1H-imidazol-1-yl)-[1,1′-biphenyl]-4-yl)-1H-tetrazole as potent and orally efficacious S-nitrosoglutathione reductase (GSNOR) inhibitors for the potential treatment of COPD

Published:2018-12 Issue:23-24 Volume:28 Page:3766-3773
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Muthukaman Nagarajan^ORCID,Deshmukh Sanjay,Tondlekar Shital,Tambe Macchindra,Pisal Dnyandeo,Sarode Neelam,Mhatre Siddharth,Chakraborti Samitabh,Shah Daisy,Bhosale Vikram M.,Kulkarni Abhay,Mahat Mahamad Yunnus A.,Jadhav Satyawan B.,Gudi Girish S.,Khairatkar-Joshi Neelima,Gharat Laxmikant A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme

2. A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans

3. S -Nitrosylation in Cardiovascular Signaling

4. Protein S-nitrosylation in health and disease: a current perspective

5. S-Nitrosoglutathione Reductase

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