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Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model

Published:2013-11 Issue:21 Volume:23 Page:5931-5935
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Matti Afnan A.,Mirzaei Joseph,Rudolph John,Smith Stephen A.,Newell Jayme L.,Patel Sarjubhai A.,Braden Michael R.,Bridges Richard J.,Natale Nicholas R.

Funder

NIH NINDS

Molecular Computational Core

NIGMS

University of Montana Graduate School

Neuroscience NSF REU

University of Idaho

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. System xc- cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS

2. Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine-Glutamate Antiporter (System xc−) to Normal and Pathological Glutamatergic Signaling

3. Glutamate and GABA Receptors and Transporters, Structure Function and Pharmacology,2002

4. Topics in Medicinal Chemistry;Bridges,2009

5. Can Selective Ligands for Glutamate Binding Proteins be Rationally Designed?

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5. Regioselective synthesis of isoxazole and 1,2,4-oxadiazole-derived phosphonates via [3 + 2] cycloaddition;Organic & Biomolecular Chemistry;2018