Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertension

Author:

Hoyt Scott B.,Taylor Jerry,London Clare,Ali Amjad,Ujjainwalla Feroze,Tata Jim,Struthers Mary,Cully Doris,Wisniewski Tom,Ren Ning,Bopp Charlene,Sok Andrea,Verras Andreas,McMasters Daniel,Chen Qing,Tung Elaine,Tang Wei,Salituro Gino,Clemas Joe,Zhou Gaochao,MacNeil Douglas,Duffy Ruth,Xiong Yusheng

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

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3. Resistant hypertension: diagnosis, evaluation, and treatment;Calhoun;Hypertension,2008

4. Aldosterone and arterial hypertension;Tomaschitz;Nat Rev Endocrinol,2010

5. Aldosterone and cardiovascular disease;Carey;Curr Opin Endocrinol Diabetes Obes,2010

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