Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors-Reference-Cited by-同舟云学术

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Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors

Published:2017-06 Issue:12 Volume:27 Page:2708-2712
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Fischer Tim,Krüger Thomas,Najjar Abdulkarim,Totzke Frank,Schächtele Christoph,Sippl Wolfgang,Ritter Christoph,Hilgeroth Andreas

Funder

Deutsche Forschungsgemeinschaft

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Deregulation of cell signaling in cancer

2. Oncogenic pathway signatures in human cancers as a guide to targeted therapies

3. Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

4. Receptor tyrosine kinases: mechanisms of activation and signaling

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Developments of Pyrrolo[2,3-d]pyrimidines with Pharmaceutical Potential;Current Organic Chemistry;2024-09

2. K2S2O8 promoted C–H direct thiocyanation of pyrrolo[2,3-d]pyrimidine derivatives with ammonium thiocyanate;Tetrahedron;2024-06

3. Structural and molecular insights from dual inhibitors of EGFR and VEGFR2 as a strategy to improve the efficacy of cancer therapy;Chemical Biology & Drug Design;2024-05

4. K2s2o8 Promoted C-H Direct Thiocyanation Of Pyrrolo[2,3-D]Pyrimidine Derivatives with Ammonium Thiocyanate;2024

5. Pyrrolo[2,3-d]pyrimidines as EGFR and VEGFR kinase inhibitors: a comprehensive SAR review;Current Medicinal Chemistry;2023-08-15

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