Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation-Reference-Cited by-同舟云学术

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Published:2017-06 Issue:12 Volume:27 Page:2721-2726
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Smith Graham F.,Altman Michael D.,Andresen Brian,Baker James,Brubaker Jason D.,Chen Hongmin,Chen Yiping,Childers Matthew,Donofrio Anthony,Ferguson Heidi^ORCID,Fischer Christian,Fischmann Thierry O.,Gibeau Craig,Hicks Alexander,Jin Sue,Kattar Sam,Kleinschek Melanie A.,Leccese Erica,Lesburg Charles,Li Chaomin,Lim Jongwon,Liu Duan,Maclean John K.F.,Mansoor Faruk,Moy Lilly Y.,Mulrooney Erin F.,Necheva Antoaneta S.,Presland Jeremy,Rakhilina Larissa,Yang Ruojing,Torres Luis,Zhang-Hoover Jie,Northrup Alan

Funder

Merck and Co. Inc.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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3. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4;Suzuki;Nature,2002

4. IRAK-4 as the central TIR signaling mediator in innate immunity;Suzuki;Trends Immunol,2002

5. Pyogenic bacterial infections in humans with IRAK-4 deficiency;Picard;Science (New York, NY),2003

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